AHA Scientific Sessions 2019 Daily News - Day 3

See You Next Year in Dallas! AHA Scientific Sessions 2020 | November 14-16, 2020 | Dallas, Texas TOP PICKS from the Program Chair AND Late-Breaking Science schedule 2 Inside AHA takes strong stand against vaping Harrington ScientificSessions.org #AHA19 MONDAY Nov. 18, 2019 November 16-18, 2019 | Philadelphia, Pennsylvania DAILY NEWS Sacubitril/valsartan associated with better outcomes in HF patients with preserved ejection fraction In a pooled analysis of 13,195 heart failure patients across the spectrum of ejection fraction, those randomized to sacubitril/ valsartan compared with a PARAGON, PARADIGM RESULTS Drug combination may reduce CV mortality in HF patients across the ejection fraction spectrum See PARAGON, PARADIGM , page 17 Revolution Network. Sönmez spoke to the heart of the fourth industrial revolution — a concept in the international community that represents the current state of rapid, simultaneous and systemic transformations driven by advances in science and technology. It’s reshaping the landscape of industry, geographic boundaries and pushing the confines of existing regulatory infrastructures. “As technology evolves, it’s changing everything,” Sönmez said. “Artificial intelligence has been elevated from limited data and now has all of our systems falling behind in the ‘too late zone.’ Yet, with it, we may be able to solve some of the biggest challenges in medicine by Murat Sönmez, World Economic Forum tackle ethics, equity and access of big data A gainst the historic backdrop of Philadelphia, Murat Sönmez charted the course for the future of big data while sharing important lessons from history. Sönmez, keynote speaker in Sunday’s Presidential Session, is managing director of the World Economic Forum and head of its Centre for the Fourth Industrial 5 renin-angiotensin-aldosterone system inhibitor had: • 16% reduction in first cardiovascular death or heart failure hospitalization • 12% reduction in all-cause mortality The PARADIGM-HF group randomized 8,399 heart failure patients with ejection fraction of 40% or lower to sacubitril/ valsartan 97/103 mg bid versus see SÖNMEZ , page 16 Researchers in Late-Breaking Science sessions on Sunday presented the pooled PARAGON-HF and PARADIGM-HF analysis and the latest results on: • Gender differences and response to treatment in heart failure patients with preserved ejection fraction • A drug that improves exercise performance with Fontan circulation • How older HF patients tolerated dapagliflozin and patients’ reported quality of life A HA President Robert Harrington used his Conner Presidential Address at Scientific Sessions on Sunday to spotlight the two pillars of his career: clinical trials and supporting the next generation of researchers. He titled his speech “Evidence Matters,” a phrase that was a drumbeat throughout his presentation during day two of the organization’s flagship conference. “Evidence matters in basic discovery science and in the translation of science from the bench to the bedside and then to the community,” said Harrington, chair of the Department of Medicine at Stanford University AHA president emphasizes importance of clinical trials, young researchers B ernard J. Tyson, a longtime supporter of the American Heart Association who helped shape the organization as a member of the Board of Directors and co-founder of the CEO Roundtable, was remembered Sunday for his devotion to improving the health and IN MEMORIAM CEO remembers Bernard Tyson for leaving health care ‘better than he found it’ see HARRINGTON , page 18 See IN MEMORIAM , page 7 Tyson Sönmez Brown